(Twinrix Adult / Twinrix Paediatric / Ambirix)
Book your slot online; no GP referral needed.
The clinician reviews your health history and confirms your schedule.
Receive first dose and schedule your remaining appointments.
Get vaccination records and advice for any future boosters.
Prevalent risks in South and Southeast Asia, sub-Saharan Africa, and South America make the combined vaccine a logical choice.
Recommended vaccines : Hepatitis A+B Combined, Typhoid, Rabies, Japanese Encephalitis
Recommended vaccines : Hepatitis A+B Combined, Typhoid, Rabies, Japanese Encephalitis
Recommended vaccines : Hepatitis A+B Combined, Yellow Fever, Typhoid, Cholera, Rabies
Spread occurs when faecal matter is ingested, often through undercooked shellfish, untreated water, or poor food hygiene. Risks are high in areas with sub-standard sanitation.
Appearing two to six weeks post-exposure, symptoms include fatigue, nausea, fever, and jaundice. Recovery can take months, and no specific antiviral treatment exists.
Hepatitis B is a highly infectious liver virus transmitted through blood, sexual contact, or unsterile medical equipment. It persists on surfaces for seven days.
The virus spreads via infected bodily fluids, often through unprotected sex, needles, or medical procedures in poorly regulated settings. Emergency care abroad presents a significant risk.
Initial infection is often asymptomatic. If symptoms occur, they include nausea, jaundice, and abdominal pain. Chronic infection in some adults leads to severe liver damage.
Twinrix Paediatric requires three doses at 0, 1, and 6 months. Alternatively, Ambirix offers a two-dose course given at 0 and 6–12 months. Your pharmacist will recommend the most suitable option for your child’s timeline.
Twinrix Adult follows a 0, 1, and 6-month schedule. Adults 18+ can use an accelerated course (0, 7, 21 days plus a 12-month booster), though this is unavailable for 16–17-year-olds. Clinicians will recommend the ideal timing based on your age and travel plans.
Side effects are typically mild and short-lived, commonly including injection site soreness, redness, swelling, headache, fatigue, or a low-grade fever. Inform your clinician of any allergies, previous vaccine reactions, or medical conditions before your appointment.
Here is a straightforward comparison to help you decide before your appointment.
Injections
3 (standard) or 4 (accelerated)
Up to 5 total
Cost
From £270 (standard) / £360 (accelerated)
From £250 across both courses
Schedule
0, 1, 6 months / 0, 7, 21 days + booster at 12 months (18+ only)
Each vaccine follows its own timeline
Best for
Adults with no prior immunity to either infection
Patients with existing immunity to one infection
Twinrix is typically the most practical option for healthy adults visiting high-prevalence areas; your clinician will determine the best route during your appointment.
Travellers to South and Southeast Asia
High infection prevalence across the region, including popular tourist spots
Travellers visiting friends and relatives
Frequent consumption of local food and stays in areas lacking standard hygiene
Long-stay travellers and expats
Long-term exposure to local food, water, and medical facilities in high-risk nations
Backpackers and budget travellers
Increased contact with local resources and higher likelihood of needing low-resource medical care
Healthcare workers and medical volunteers
Direct exposure to blood, fluids, and contaminated food/water in high-risk settings
Those seeking medical or dental care abroad
Risk of blood-borne exposure where sterilisation standards may be inconsistent
Travellers with pre-existing liver conditions
Prior liver conditions significantly raise the risk of severe infection complications
Since qualifying as a pharmacist in 2006, Mandeep Sandhu has turned travel health into his life’s work. As an independent prescriber with expert NaTHNaC and Yellow Fever credentials, he focuses on giving you genuine peace of mind before you fly.
Mandeep is an avid traveler himself, so he knows that travel health isn’t a “one-size-fits-all” process. He rejects the generic checklist approach, preferring to sit down with you to discuss your unique plans. Whether you’re heading on a family holiday or a remote adventure, Mandeep provides the personal, professional care you deserve.
A fully GPhC-registered pharmacist.
Qualified to independently prescribe and provide travel medicines
Accredited Yellow Fever centre providing vaccinations and official ICVP documentation.
Specialist travel health education following national UK standards
Real experiences from patients who trusted our Medway travel clinic for their vaccinations and travel health advice.
Twinrix is a 2-in-1 vaccine protecting against Hepatitis A and B. It uses a 0, 1, and 6-month schedule, matching the separate Hepatitis B course while covering both infections in one series. For travellers requiring dual protection, this combined course is often more practical than two separate vaccine sets.
No. Twinrix is unsuitable for post-exposure care. If recently exposed via needles, blood, or sexual contact, contact your GP or visit A&E immediately for specialist assessment.
Yes. Children aged 1–15 can have Twinrix Paediatric (three doses) or Ambirix (two doses, 6–12 months apart). Your clinician will recommend the right option.
A full course offers up to 25 years of Hepatitis A protection and long-term Hepatitis B immunity, rarely requiring boosters for healthy adults. Start early to ensure completion before travel.
